De facto standards are still standards, if you like it or not.
“(…) the reality is that too often, resources are spent on making the site look great or creating an innovative widget, and usability is neglected until the very end of development (if it’s even ever looked at). Ideally, you’ll be doing testing throughout the project, be it testing your information architecture, creating and testing wireframes and paper prototypes, and conducting usability tests with real users on all the devices that you’re targeting with your design, all with enough time before the launch so that you can iterate your designs and test them again.”
(Katie Sherwin a.k.a. @kwsherwin ~ Nielsen Norman Group)