“Grid system design should begin with a constraint. Something that is knowable and unchangeable. This constraint is used to build the modules of your grid. In book design, that constraint is defined by the page through subdivision. Book designers take the page, divide it up into a modular grid of spaces. These spaces (called modules) are then combined to create rows and columns. These are then filled with content (images and text). The text feels like it belongs because the columns are related to the physical object: the page. (…) Embrace the fluidity of the web. Design layouts and systems that can cope to whatever environment they may find themselves in. But the only way we can do any of this is to shed ways of thinking that have been shackles around our necks. They’re holding us back. Start designing from the content out, rather than the canvas in.
” (Mark Boulton